Matrix compatible solid phase microextraction coating, a greener approach to sample preparation in vegetable matrices

• Overcoated fiber provides solventless automated solution for complex food matrices.
• The coating was evaluated by DI-SPME under challenging analytical conditions.
• PDMS/DVB/PDMS fiber showed significant analytical advancements.
• PDMS/DVB/PDMS fiber open new prospects toward greener high-throughput protocols.

This work proposes the novel PDMS/DVB/PDMS fiber as a greener strategy for analysis by direct immersion solid phase microextraction (SPME) in vegetables. SPME is an established sample preparation approach that has not yet been adequately explored for food analysis in direct immersion mode due to the limitations of the available commercial coatings. The robustness and endurance of this new coating were investigated by direct immersion extractions in raw blended vegetables without any further sample preparation steps. The PDMS/DVB/PDMS coating exhibited superior features related to the capability of the external PDMS layer to protect the commercial coating, and showed improvements in terms of extraction capability and in the cleanability of the coating surface. In addition to having contributed to the recognition of the superior features of this new fiber concept before commercialization, the outcomes of this work serve to confirm advancements in the matrix compatibility of the PDMS-modified fiber, and open new prospects for the development of greener high-throughput analytical methods in food analysis using solid phase microextraction in the near future.