کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1188544 963491 2008 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Iron-chelating ability and antioxidant properties of phycocyanin isolated from a protean extract of Spirulinaplatensis
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Iron-chelating ability and antioxidant properties of phycocyanin isolated from a protean extract of Spirulinaplatensis
چکیده انگلیسی

The invitro scavenger activities of different reactive oxygen species (superoxide radical, hydroxyl radical, hydrogen peroxide, hypochlorous acid and peroxyl radical), the effects on lipid peroxidation and the iron-chelating ability of a Spirulinaplatensis protean extract and the biliprotein, phycocyanin, isolated from this microalga were studied. S. platensis protean extract inhibited the generation of hydroxyl radical (IC50 = 537 μg/ml for the system with EDTA and 1500 μg/ml without EDTA), the production of peroxyl radical (IC50 = 230 μg/ml), and the lipid peroxidation process (IC50 = 2320 μg/ml for the enzymatic system and 2180 μg/ml for the non-enzymatic system). Besides, phycocyanin inhibited hydroxyl and peroxyl radicals and the lipid peroxidation process. The iron ions decreased the maximum fluorescence emission spectra of S. platensis protean extract and phycocyanin and it was an indicator of the metal-chelating activity. The antioxidant properties of S. platensis and phycocyanin may arise from both radical-scavenging and metal chelation. Our results suggest that S. platensis could be used as a dietary supplement to prevent some diseases where free radicals are involved.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 110, Issue 2, 15 September 2008, Pages 436–445
نویسندگان
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