کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1189387 963511 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
New benzenoids and anti-inflammatory constituents from Zanthoxylum nitidum
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
New benzenoids and anti-inflammatory constituents from Zanthoxylum nitidum
چکیده انگلیسی

Zanthoxylum nitidum is commercially used in healthcare products for the improvement of tooth condition. Its fruit is also used as a spice. Three new benzenoids, (E)-4-(4-hydroxy-3-methylbut-2-enyloxy)benzaldehyde (1), (E)-methyl 3-(4-((E)-4-hydroxy-3-methylbut-2-enyloxy)phenyl)acrylate (2), and (Z)-methyl 3-(4-((E)-4-hydroxy-3-methylbut-2-enyloxy)phenyl)acrylate (3), have been isolated from the stem wood of Z. nitidum, together with 17 known compounds (4–20). The structures of these new compounds were determined through spectroscopic and MS analyses. Compounds 8–10, 13, 14, 17, and 18 exhibited inhibition (IC50 ⩽ 7.95 μg/ml) of superoxide anion generation by human neutrophils in response to formyl-l-methionyl-l-leucyl-l-phenylalanine/cytochalasin B (fMLP/CB). Compounds 7–9, 13, 14, and 17 inhibited fMLP/CB-induced elastase release with IC50 values ⩽7.45 μg/ml.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 125, Issue 2, 15 March 2011, Pages 282–287
نویسندگان
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