کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1190226 963527 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Acetylcholinesterase inhibitory-active components of Rhodiola rosea L.
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Acetylcholinesterase inhibitory-active components of Rhodiola rosea L.
چکیده انگلیسی

An activity-directed fractionation and purification process was used to identify the acetylcholinesterase inhibitory-active components of Rhodiola rosea L. (RR). Dried rhizome of RR was extracted with boiled ethanol. After removal of tannins, the extract was separated into chloroform, ethyl acetate, n-butanol and water fractions. Among these, chloroform and n-butanol fractions showed stronger activity by bioassay for anti-cholinesterase activity than did ethyl acetate and water fractions. The chloroform fraction was then subjected to separation and purification using silica gel column chromatography and Sephadex LH-20 chromatography. One compound, showing strong anti-cholinesterase activity, was identified by spectral methods (NMR, UV and MS) and by comparison with authentic samples. It proved to be hydroquinone.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 105, Issue 1, 2007, Pages 24–27
نویسندگان
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