Simultaneous determination of pesticide multiresidues in white wine and rosé wine by SDME/GC-MS

• It is a fast robust comprehensive and efficient method for the determination of pesticide residues in white and rosé wine samples.
• Tests showed that the extraction by SDME was comprehensive for use in aqueous or alcoholic matrix (alcohol content up to 15%).
• This methodology presents high sensitivity for detecting and quantifying eleven pesticides up to 65 μg L− 1 in the samples.

Pesticides have been applied in vineyards around the world in order to protect grapevines against different diseases. However, the indiscriminate use of these substances has aroused great concern regarding the health and safety of consumers due to toxicological risks that pesticides may present to human health. Thus, this study aims to determine simultaneously eighteen pesticide residues from different chemical classes in real white wine and rosé wine samples using single-drop microextraction (SDME), followed by gas chromatography coupled to mass spectrometry (GC-MS). The step of SDME was optimized, and it was found that the best experimental conditions were as follows: toluene, 30 min extraction, 1.0 μL drop volume, solution volume 10 mL, stirring speed 200 rpm, with acidification of the medium with HCl and without the addition of salt. The proposed extraction method was efficient for the extraction of pesticides, both from aqueous solutions and from alcoholic solutions, with an ethanol concentration of up to 15%. The method was applied to real white wine and rosé wine samples, and 11 pesticide residues were detected (carbofuran, molinate, diazinon, disulfoton, malathion, endosulfan, ethion, bifenthrin, permethrin I, permethrin II and azoxystrobin) with concentrations, which ranged from not detected to 65.3 μg L− 1.