Novel coumarin-based fluorescent probe for selective detection of Cu(II)

• A new fluorescent chemosensor for Cu2+ has been reported.
• We designed and synthesized a new carboxamide coumarin sensor through microwave irradiation.
• The association constant between 3 and Cu2+ was found to be 3.01 × 104 M−1.

We report an efficient and convenient method for preparing nitro-3-carboxamide coumarin derivatives, proposed as novel fluorescent chemosensor, through microwave irradiation. This compound can be used as fluorescent probe for Cu2+ with selectivity over other metal ions in aqueous solution. The fluorescence of 6-nitro-N-[2-(dimethylamino)ethyl]-2-oxo-2H-chromene-3-carboxamide(3) is the highest in the presence of Cu2+, with stronger excitation at λ = 320 nm than for the other cations tested.

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