Convenient and selective “off–on” detection nitric oxide in solution and thin film with quinoline based fluorescence sensor

• A naphthalene-sulfonamino-quinoline based copper(II) complex has been synthesized to effective probe nitric oxide (NO) in solution and thin film.
• The complex has potential application to meet the detection requirements of a NO assay.

Quinoline based fluorescence sensor (1) was synthesized and characterized with mass spectra (MS), 1H nuclear magnetic resonance (1H NMR) spectrometer, elemental analyses, and infrared (IR) spectra. Following fluorescence experiments demonstrate 1 can coordinate with copper ions, and lead to fluorescence completely quenched. The 1-copper complex was used as a “turn-on” fluorescence biosensor to convenient and highly effective detect nitric oxide (NO) over other radicals in solution and PCL-based thin film. The finding would enable the quinoline based fluorescence probe to be an “off–on” convenient NO fluorescence probe.

A naphthalene-sulfonamino-quinoline based copper(II) complex has been synthesized to effective probe nitric oxide (NO) in solution and thin film. The complex has potential application to meet the detection requirements of a NO assay.Figure optionsDownload as PowerPoint slide