A facile channel for D-glucose detection in aqueous solution

• Three new ensembles for D-glucose detection are constructed.
• These sensing ensembles are comprised of dye NAHBDS and quenchers BBVs.
• Fluorescence reversible signals for D-glucose sensing are observed.
• These ensembles show highly sensitive for D-glucose detection.
• This research can provide a new strategy for molecular recognition.

Three facile ensembles for sensing D-glucose are designed and constructed. The ensembles are comprised of fluorescent dye (NAHBDS) and boronic acid substituted viologens (BBVs) quenchers/receptors. The sensing processes of three ensembles (NAHBDS/o-BBV, NAHBDS/m-BBV and NAHBDS/p-BBV) to D-glucose were determined by fluorescence spectra at pH 7.4 buffer solution. The results show that NAHBDS/o-BBV and NAHBDS/m-BBV ensembles embody higher sensitivity for D-glucose with reversible “on–off” fluorescence response. More importantly, the recovery of relative intensity has good linear relation to low concentration of D-glucose. The action between the ensemble with D-glucose is dynamically reversible equilibrium process. The research results provide a new mode to design highly selective probe.

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