Interactions of CT-DNA with Hypocrellin A and its Al3+-Hypocrellin A complex

► The formation of 1:1 Al3+-HA complex have been chelated in water solution. ► HA and Al3+-HA complex could bind to CT DNA by intercalation mode. ► CT DNA quench the fluorescence of HA and Al3+-HA by static process. ► The binding affinity and fraction of Al33+-HA to CT DNA are stronger than HA.