Carbazole incorporated ratiometric chemosensor for Zn2+

An electron donating carbazole incorporated thiazole (3) based Zn2+ selective intrinsic chemosensor has been synthesized and investigated. It was found that electron donating substituents such as methyl and carbazole on chemosensor (1) produce remarkable red shift in emission upon complexation with Zn2+. The sensor shows a selective fluorescence response with Zn2+ over biologically relevant cations (Ca2+, Mg2+, Na+, and K+) and biologically non-relevant cations (Cd2+, In3+ and Ga3+) in an aqueous ethanol system. It also produce an enhancement in the quantum yield and a longer emission wavelength shift on Zn2+ binding with the potential of a ratiometric assay.

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► An electron donating carbazole incorporated thiazole-based chemosensor was prepared.
► Sensor showed a selective fluorescence response with Zn2+ in an aqueous ethanol system.
► It also produce an enhancement in the quantum yield.
► Probe produced a longer emission wavelength shift on Zn2+ binding with the potential of a ratiometric assay.