کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1234288 1495244 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A highly sensitive and selective assay of doxycycline by dualwavelength overlapping resonance Rayleigh scattering
ترجمه فارسی عنوان
یک آزمایش بسیار حساس و انتخابی از داکسی سایکلین با پراکندگی رقیقی تضاد دوطرفه
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی


• A rapid assay of doxycycline was performed.
• Dual-wavelength overlapping resonance Rayleigh scattering was employed.
• The detection limit (1.1 nmol L−1) was lower than or comparable to most of the reported methods.
• The generating mechanisms of multi-response RRS signals were proposed.
• A semi-empirical principle was established for better design of multi-response RRS probes.

A dual-wavelength overlapping resonance Rayleigh scattering (DWO–RRS) method was developed and validated for highly sensitive and selective assay of doxycycline residues in several meat samples. The response signals were dependent on the specific multi-site coordination between lanthanum(III) and doxycycline (DOTC). And La(III)–DOTC complex would further aggregate to form [La(III)–DOTC]n nanoparticles, resulting in the occurrence of two new scattering peaks. Notably, with the addition of DOTC, the increments of both of these two wavelengths were proportional to the concentration of DOTC over the ranges of 3.9–4.0 × 103 nmol L−1 (1.7–1.8 × 103 μg/kg). The detection limit of DWO–RRS was 1.1 nmol L−1 (0.5 μg/kg), which was lower than or comparable to most of the published methods. Additionally, the generating mechanisms of multi-response RRS signals were discussed and a semi-empirical principle was established for better design of multi-response RRS probes.

A dual-wavelength overlapping resonance Rayleigh scattering (DWO-RRS) methodology based on the specific multi-site coordination between lanthanum(III) and doxycycline (DOTC) has been successfully designed (rather than accidently encountered) for highly sensitive and selective assay of doxycycline in several meat samples.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy - Volume 124, 24 April 2014, Pages 237–242
نویسندگان
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