کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1236683 | 968873 | 2010 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Solid state and solution study of some phosphoramidate derivatives containing the P(O)NHC(O) bifunctional group: Crystal structures of CCl2HC(O)NHP(O)(NCH3(CH2C6H5))2, p-ClC6H4C(O)NHP(O)(NCH3(CH2C6H5))2, CCl2HC(O)NHP(O)(N(CH2C6H5)2)2 and p-BrC6H4C(O)NHP(O
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
Synthetic methods for several novel phosphoramidate compounds containing the P(O)NHC(O) bifunctional group were developed. These compounds with the general formula R1C(O)NHP(O)(N(R2)(CH2C6H5))2, where R1 = CCl2H, p-ClC6H4, p-BrC6H4, o-FC6H4 and R2 = hydrogen, methyl, benzyl, were characterized by several spectroscopic methods and analytical techniques. The effects of phosphorus substituents on the rotation rate around the P-Namine bond were also investigated. 1H NMR study of the synthesized compounds demonstrated that the presence of bulky groups attached to the phosphorus center and electron withdrawing groups in the amide moiety lead to large chemical-shift non-equivalence (ÎδH) of diastereotopic methylene protons. The crystal structures of CCl2HC(O)NHP(O)(NCH3(CH2C6H5))2, p-ClC6H4C(O)NHP(O)(NCH3(CH2C6H5))2, CCl2HC(O)NHP(O)(N(CH2C6H5)2)2 and p-BrC6H4C(O)NHP(O)(N(CH2C6H5)2)2 were determined by X-ray crystallography using single crystals. The coordination around the phosphorus center in these compounds is best described as distorted tetrahedral and the P(O) and C(O) groups are anti with respect to each other. In the compound Br-C6H4C(O)NHP(O)(N(CH2C6H5)2)2 (with two independent molecules in the unit cell), two conformers are connected to each other via two different N-Hâ¯O hydrogen bonds forming a non-centrosymmetric dimer. In the crystalline lattice of other compounds, the molecules form centrosymmetric dimers via pairs of same N-Hâ¯O hydrogen bonds. The structure of CCl2HC(O)NHP(O)(N(CH2C6H5)2)2 reveals an unusual intramolecular interaction between the oxygen of CO group and amine nitrogen.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy - Volume 75, Issue 4, April 2010, Pages 1236-1243
Journal: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy - Volume 75, Issue 4, April 2010, Pages 1236-1243
نویسندگان
Saeed Dehghanpour, Richard Welter, Aliou Hamady Barry, Farzaneh Tabasi,