کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1237095 | 968883 | 2009 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: A novel fluorescent assay for edaravone with aqueous functional CdSe quantum dots A novel fluorescent assay for edaravone with aqueous functional CdSe quantum dots](/preview/png/1237095.png)
Aqueous thiol-capped CdSe QDs with a narrow, symmetric emission were prepared under a low temperature. Based on the fluorescence enhancement of thiol-stabilized CdSe quantum dots (QDs) caused by edaravone, a simple, rapid and specific quantitative method was proposed to the edaravone determination. The concentration dependence of fluorescence intensity followed the binding of edaravone to surface of the thiol-capped CdSe QDs was effectively described by a modified Langmuir-type binding isotherm. Factors affecting the fluorescence detection for edaravone with thiol-stabilized CdSe QDs were studied, such as the effect of pH, reaction time, the concentration of CdSe QDs and so on. Under the optimal conditions, the calibration plot of C/(I − I0) with concentration of edaravone was linear in the range of (1.45–17.42) μg/mL (0.008–0.1 μmol/L) with correlation coefficient of 0.998. The limit of detection (LOD) (3σ/κ) was 0.15 μg/mL (0.0009 μmol/mL). Possible interaction mechanism was discussed.
Journal: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy - Volume 72, Issue 5, June 2009, Pages 1066–1070