Graphite oxide-catalyzed acetylation of alcohols and phenols

Graphite oxide (GO) was used as a catalyst for the reactions of alcohols and phenols with acetic anhydride. The acetates of primary and secondary alcohols were prepared in good to excellent yields in short reaction time under mild conditions. Electron deficient phenols could be converted to the corresponding acetates steadily. As an efficient catalyst, GO is easily available, cheap, moderately toxic and weakly acidic.

Graphite oxide could work as a highly efficient catalyst for the acetylation of alcohols and phenols with acetic anhydride.Figure optionsDownload as PowerPoint slide