کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1254116 | 971345 | 2014 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: An efficient one-pot synthesis of thiophene-fused pyrido[3,2-a]azulenes via Gewald reaction An efficient one-pot synthesis of thiophene-fused pyrido[3,2-a]azulenes via Gewald reaction](/preview/png/1254116.png)
A simple and efficient procedure was developed for the synthesis of 11H(2H)-4-oxothiophene[3′,4′:6,5]pyrido[3,2-a]azulene-10-carboxylates (3) in moderate to good yields via the Gewald reaction of ethyl 1-cyanoacetyl-2-methoxyazulene-3-carboxylate (1) with carbonyl compounds (2) and elemental sulfur utilizing imidazole as catalyst. This reaction provides a new procedure for synthesis of pyridinone-fused azulenes.
A simple and efficient procedure was developed for the synthesis of 11H(2H)-4-oxothiophene[3′,4′:6,5]pyrido[3,2-a]azulene-10-carboxylates (3) in moderate to good yields via Gewald reaction of ethyl 1-cyanoacetyl-2-methoxyazulene-3-carboxylate (1) with carbonyl compounds (2) and elemental sulfur utilizing imidazole as catalyst. This reaction provides a new procedure for synthesis of pyridinone-fused azulenes.Figure optionsDownload as PowerPoint slide
Journal: Chinese Chemical Letters - Volume 25, Issue 12, December 2014, Pages 1591–1594