کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1254403 971373 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
PEGylated WS2 nanosheets for X-ray computed tomography imaging and photothermal therapy
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
PEGylated WS2 nanosheets for X-ray computed tomography imaging and photothermal therapy
چکیده انگلیسی

WS2 nanosheets were prepared by the solvent-thermal method in the presence of n-butyl lithium, then the exfoliation under the condition of ultrasound. The formed WS2 nanosheets were conjugated with thiol-modified polyethylene glycol (PEG-SH) to improve the biocompatibility. The nanosheets (WS2-PEG) were able to inhibit the growth of a model HeLa cancer cell line in vitro due to the high photothermal conversion efficiency of ∼35% irradiated by an 808 nm laser (1 W/cm2). As a proof of concept, WS2-PEG nanosheets with the better X-ray attenuation property than the clinical computed tomography (CT) contrast agent (Iohexol) could be performed for CT imaging of the lymph vessel.

The WS2-PEG nanosheets have the high photothermal conversion efficiency and show a good X-ray attenuation property.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 26, Issue 6, June 2015, Pages 749–754
نویسندگان
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