Polypropylene non-woven supported fibronectin molecular imprinted calcium alginate/polyacrylamide hydrogel film for cell adhesion

Fibronectin (FN) imprinted polypropylene (PP) non-woven supported calcium alginate/polyacrylamide hydrogel film (PP-s-CA/PAM MIP) was prepared using non-woven PP fiber as matrix, FN as template molecule, sodium alginate (SA) and acrylamide (AM) as functional monomers, via UV radiation-reduced polymerization. The PP-s-CA/PAM MIP exhibited an obvious improvement in terms of adsorption capacity for FN compared with non-imprinted polymer (NIP). The PP-s-CA/PAM MIP was successfully used for the culture of mouse fibroblast cells (L929) and the results showed that PP-s-CA/PAM MIP exhibited better cell adherence performance than the NIP did.

Fibronectin (FN) imprinted polypropylene (PP) non-woven supported calcium alginate/polyacrylamide hydrogel film (FN-MIP) was prepared using non-woven PP fiber as matrix, FN as template molecule, sodium alginate (SA) and acrylamide (AM) as functional monomers. The FN-MIP exhibited better cell adherence performance than the non-imprinted polymer (NIP) did.Figure optionsDownload as PowerPoint slide