Preparation and chiral recognition of a novel chiral stationary phase for HPLC, based on mono(6A-N-1-(2-hydroxyl)-phenylethylimino-6A-deoxy)-β-cyclodextrin and covalently bonded silica gel

A novel chiral stationary phase (CSP) was prepared by immobilizing mono(6A-N-1-(2-hydroxyl)-phenylethyl-imino-6A-deoxy)-β-cyclodextrin onto the surface of silica gel via a longer spacer. This chiral stationary phase exhibited good enantioselectivity for a variety of chiral compounds under reversed-phase conditions.