کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1256170 971457 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Protein surface recognition of the novel tetra-carboxylphenyl calix[4]arene to cytochrome c
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Protein surface recognition of the novel tetra-carboxylphenyl calix[4]arene to cytochrome c
چکیده انگلیسی

The interaction of the novel tetra-carboxylphenyl calix[4]arene (TCPC) with the bovine heart cytochrome c (Cc) was first investigated by fluorescence spectroscopy and molecular modeling methods. The formation of a stable 1:1 complex was monitored by fluorescence titration, and its binding constant is 1.916 × 107 L mol−1. Molecular modeling reveals the recognition mechanism of TCPC to the Cc surface, that is, the electrostatic interaction drives TCPC to the Cc surface, and the van der Waals interaction orientates TCPC parallel to the cleft of Cc.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 19, Issue 11, November 2008, Pages 1341–1344
نویسندگان
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