Microwave-assisted synthesis of asymmetric thiocarbonohydrazones under solvent-free conditions

Six new asymmetric thiocarbonohydrazones 3a–3f were synthesized from following steps: firstly hydrazine hydrate reacted with carbon disulfide to form thiocarbonohydrazide (1) under microwave irradiation. Then compound (1) reacted with ketone and different aldehydes step by step to give 3a–3f with excellent yields under solvent-free conditions using microwave irradiation. Their structures have been determined by elemental analysis, IR, MS and 1H NMR data.