کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1257556 | 971569 | 2012 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis of oleanolic disaccharide derivatives
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Oleanolic acid 1 exists widely in food, medicinal herbs and other plants and possesses many attractive biological activities. Recently, some oleanolic derivatives were reported to have interesting anti-tumor activities. Herein, using association principle of drug design, OA disaccharide 17 was designed and synthesized by coupling a-L-rhamnopyranosyl-(1â2)-a-L-arabinopyranosyl disaccharide moiety, which has proved to be a unique sugar sequence with strongly antitumor activity, and modified OA with a nitrile at C-17.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 23, Issue 4, April 2012, Pages 403-406
Journal: Chinese Chemical Letters - Volume 23, Issue 4, April 2012, Pages 403-406
نویسندگان
Shu Chen Pei, Jian Bo Wu, Fan Lei, Shan Qian, Li Hai, Yong Wu,