کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1267252 1496927 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A novel voltammetric sensor for amoxicillin based on nickel–curcumin complex modified carbon paste electrode
موضوعات مرتبط
مهندسی و علوم پایه شیمی الکتروشیمی
پیش نمایش صفحه اول مقاله
A novel voltammetric sensor for amoxicillin based on nickel–curcumin complex modified carbon paste electrode
چکیده انگلیسی

The electrocatalytic oxidation of amoxicillin was investigated on a nickel-based (Ni(II)–curcumin) chemically modified electrode. This modified electrode was prepared by electropolymerization of complex (curcumin = 1,7-bis[4-hydroxyl-3-methoxyphenyl]-1,6-heptadiene-3,5-dione) in alkaline solution. For the first time, the catalytic oxidation of amoxicillin was demonstrated by cyclic voltammetry, chronoamperometry, chronocoulometry and amperometry methods at the surface of this modified carbon paste electrode. The obtained results showed that NiOOH acts as an electrocatalyst for oxidation of amoxicillin. This electrocatalytic oxidation exhibited a good linear response for amoxicillin concentration over the range of 8 × 10−6–1 × 10−4 M with a detection limit of 5 × 10−6 M. Therefore, this electrocatalytic method was used as a simple, selective and rapid method able to determine amoxicillin in pharmaceutical preparations and biological media.


► A nickel-based (Ni(II)-curcumin) chemically modified electrode was prepared.
► Electrocatalytic oxidation of amoxicillin was investigated on modified electrode.
► Preparation of our modified electrode is very simple, easy and cheap.
► Up to now, electrocatalytic oxidation of amoxiciline wasn't reported in literatures.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioelectrochemistry - Volume 85, June 2012, Pages 44–49
نویسندگان
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