کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1268918 | 972428 | 2008 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Apoferritin as a bionanomaterial to facilitate the electron transfer reactivity of hemoglobin and the catalytic activity towards hydrogen peroxide Apoferritin as a bionanomaterial to facilitate the electron transfer reactivity of hemoglobin and the catalytic activity towards hydrogen peroxide](/preview/png/1268918.png)
In this report, apoferritin as a stable bionanomaterial was modified with hemoglobin on pyrolytic graphite electrode. Rapid electron transfer reactions of hemoglobin were achieved with the help of apoferritin in a large pH range. Moreover, hemoglobin as an enzyme exhibits fine electrocatalytic activity towards the reaction of hydrogen peroxide, and a wide concentration range of linear relationship between the reduction peak current and the concentration of hydrogen peroxide has been obtained with a higher upper detection limit, which may be further developed for a hydrogen peroxide biosensor. Therefore, a new property of apoferritin is explored, in which apoferritin works as a bionanomaterial to be an accelerant of the electron transfer of Hb and a stabilizer to retain the catalytic ability of the protein under mal-condition.
Journal: Bioelectrochemistry - Volume 72, Issue 1, February 2008, Pages 77–80