کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1272288 972554 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Poly(amidosulfonic acid) modified glassy carbon electrode for determination of isoniazid in pharmaceuticals
موضوعات مرتبط
مهندسی و علوم پایه شیمی الکتروشیمی
پیش نمایش صفحه اول مقاله
Poly(amidosulfonic acid) modified glassy carbon electrode for determination of isoniazid in pharmaceuticals
چکیده انگلیسی

Amidosulfonic acid was electropolymerized by cyclic voltammetry onto the surface of glassy carbon electrode (GCE) to fabricate the chemically modified electrode, which showed high stability, good selectivity and reproducibility for determination of isoniazid. The modified electrode showed an excellent electrocatalytical effect on the oxidation of isoniazid. Under the optimum conditions, there was a good linear relationship between anodic peak current and isoniazid concentration in the range of 5.0 × 10−8– 1.0 × 10−5 M, and a detection limit of 1.0 × 10−8 M (S/N = 3) was obtained after 120 s at the accumulation potential of − 0.2 V (vs. SCE). This developed method had been applied to the direct determination of isoniazid in injection and tablet samples with satisfactory results.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioelectrochemistry - Volume 73, Issue 1, June 2008, Pages 37–42
نویسندگان
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