کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1315321 976018 2006 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules
چکیده انگلیسی

Advances in the development of newly developed fluorinated drugs, approved or in clinical trials, as organized by biological targets/disease states, are reviewed. In a few cases, compounds in early stages of development will be discussed, particularly where new promising targets are involved. Important topics such as anticancer and antiviral drugs were covered in the two previous reviews in this series. Included herein will be fluorinated drugs for treatment of diseases of the central nervous system, various cardiovascular diseases and obesity, antibacterial agents, and antifungal therapy.

New fluorine-containing drugs continue to be developed and marketed for a broad spectrum of applications. Expanded opportunities for the application of fluorine in medicinal chemistry have appeared with the identification of new targets for drug action. Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Fluorine Chemistry - Volume 127, Issue 8, August 2006, Pages 1013–1029
نویسندگان
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