کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1337195 | 1500277 | 2013 | 6 صفحه PDF | دانلود رایگان |

Synthesis, structural and spectroscopic characterizations, molecular modeling and antimycobacterial assays of new silver(I) complexes with two Schiff bases – MBDA and MBDB – are reported. The complexes [Ag(MBDA)2]NO3, or AgMBDA, and [Ag(MBDB)NO3] or AgMBDB, were obtained by the reaction of the respective ligands with silver(I) nitrate in methanol. The Schiff bases were previously obtained by mixing ethylenediamine or 1,3-diaminopropane with p-anisaldehyde. The characterizations of the complexes were based on elemental (C, H and N) and thermal (TG-DTA) analyses and 13C and 1H NMR and FT-IR spectroscopic measurements, as well as X-ray structure determination for AgMBDA. Spectroscopic data predicted by DFT calculations are in agreement with the experimental data for the AgMBDA complex. The AgMBDA complex has a monomeric structure with a molar proportion 1:2 Ag/ligand, while AgMBDB presents a 1:1 proportion. The complexes AgMBDA and AgMBDB showed to be more effective against Mycobacterium tuberculosis than antibacterial agent silver sulfadiazine – SSD.
Two new silver(I) complexes of two Schiff bases were synthesized. Antimycobacterial studies were evaluated and the silver complexes showed high activity against Mycobacterium tuberculosis, reporting a more potent activity action than commercial Silver Sulfadiazine compound. Full characterization was performed to two complexes.Figure optionsDownload as PowerPoint slide
Journal: Polyhedron - Volume 62, 7 October 2013, Pages 104–109