کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1338610 | 979672 | 2013 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Highly regioselective conversion of epoxides to β-hydroxy nitriles using metal(II) Schiff base complexes as new catalysts under mild conditions Highly regioselective conversion of epoxides to β-hydroxy nitriles using metal(II) Schiff base complexes as new catalysts under mild conditions](/preview/png/1338610.png)
Epoxides undergo efficient ring opening with potassium cyanide in acetonitrile in the presence of metal Schiff base complexes as catalysts. This method was carried out under neutral and mild conditions with both high yields and high regioselectivity within a short period of time. Thus, several β-hydroxy nitriles, useful intermediates for the synthesis of biologically active molecules, were easily obtained at room temperature.
In this research, ring opening of epoxides with potassium cyanide in the presence of metal Schiff base complexes as new catalysts under neutral and mild conditions is described. With this protocol, β-hydroxy nitriles were obtained in high yields and high regioselectivity within a short period of time.Figure optionsDownload as PowerPoint slide
Journal: Polyhedron - Volume 49, Issue 1, 25 January 2013, Pages 234–238