کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1362563 | 981490 | 2010 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: A synergistic hydrophobic effect against resistant bacteria
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: A synergistic hydrophobic effect against resistant bacteria Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: A synergistic hydrophobic effect against resistant bacteria](/preview/png/1362563.png)
چکیده انگلیسی
Incorporation of an hydrophobic (phenethylamino)ethyl ether at C2″ of N1-(HABA)-3′,4′-dideoxyparomomycin led to a novel analog with an excellent antibacterial profile against a host of resistant bacteria.
Incorporation of an hydrophobic (phenethylamino)ethyl ether at C2″ of N1-(HABA)-3′,4′-dideoxyparomomycin led to a novel analog with an excellent antibacterial profile against a host of resistant bacteria.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 20, Issue 23, 1 December 2010, Pages 7097–7101
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 20, Issue 23, 1 December 2010, Pages 7097–7101
نویسندگان
Stephen Hanessian, Kandasamy Pachamuthu, Janek Szychowski, Alexandre Giguère, Eric E. Swayze, Michael T. Migawa, Boris François, Jiro Kondo, Eric Westhof,