Thiazole analog as stearoyl-CoA desaturase 1 inhibitor

SCD1 inhibition may represent a novel treatment for obesity, type-2 diabetes and related metabolic disorders. A prototype thiazole amide analog 13 (MF-152) was identified as an excellent tool in the study of SCD biology in animals.

A prototype thiazole amide analog 13 (MF-152) was identified as an excellent tool in the study of SCD biology in animals.Figure optionsDownload as PowerPoint slide