کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1366061 981580 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and antibacterial activity of novel oxazolidinones with methylene oxygen- and methylene sulfur-linked substituents at C5-position
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis and antibacterial activity of novel oxazolidinones with methylene oxygen- and methylene sulfur-linked substituents at C5-position
چکیده انگلیسی

Novel oxazolidinone derivatives of the lead compound RBx 8700, containing methylene oxygen- and methylene sulfur-linked substituents at the C5-position, were synthesized. Antibacterial screening of these compounds against a panel of resistant and susceptible Gram-positive and fastidious Gram-negative bacteria gave compounds 2 and 4 as new antibacterial agents.

Novel oxazolidinone derivatives of the lead compound RBx 8700 containing methylene oxygen- and methylene sulfur-linked substituents at C5-position were synthesized and their biological activity reported.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 17, Issue 17, 1 September 2007, Pages 4778–4783
نویسندگان
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