Novel ebselen–porphyrin conjugates: Synthesis and nucleic acid interaction study

Novel porphyrins bearing ebselen (2-phenyl-1,2-benzisoselenazol-3[2H]-one) moiety were synthesized and characterized. Their interactions with herring sperm DNA were studied by means of UV–visible, fluorescence, circular dichroism spectroscopy, and gel electrophoresis.

The synthesis and DNA interaction of novel ebselen–porphyrin conjugates is reported.Figure optionsDownload as PowerPoint slide