Novel aminoethylbiphenyls as 5-HT7 receptor ligands

The synthesis of a series of aminoethylbiphenyls as novel 5-HT7 receptor ligands is described. The novel derivatives exhibit high affinity for the 5-HT7 receptor with selectivity toward 5-HT1A receptor.

The synthesis of novel aminoethylbiphenyls with high affinity for the 5-HT7 receptors and good selectivity towards 5-HT1A receptors is reported.Figure optionsDownload as PowerPoint slide