Phosphonoxins: Rational design and discovery of a potent nucleotide anti-Giardia agent

Phosphonoxins, a new class of synthetic, rationally designed anti-microbial agents, are described. From this class a sub-micromolar inhibitor of Giardia trophozoite growth has been identified.

Phosphonoxins, a new class of synthetic, rationally designed anti-microbial agents, are described. From this class a sub-micromolar inhibitor of Giardia trophocoite growth has been identified.Figure optionsDownload as PowerPoint slide