کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1367383 981630 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Conjugated indole-imidazole derivatives displaying cytotoxicity against multidrug resistant cancer cell lines
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Conjugated indole-imidazole derivatives displaying cytotoxicity against multidrug resistant cancer cell lines
چکیده انگلیسی

We report herein the SAR studies of a series of indole-imidazole compounds. that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes. The in vitro cytotoxic effects have been demonstrated across a wide array of tumor types, including hematologic and solid tumor cell lines of various origins (e.g., leukemia, breast, colon, and uterine).

We report herein the SAR studies of a series of indole-imidazole compounds. that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes. The in vitro cytotoxic effects have been demonstrated across a wide array of tumor types, including hematologic and solid tumor cell lines of various origins (e.g., leukemia, breast, colon, and uterine).Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 19, 1 October 2006, Pages 5164–5168
نویسندگان
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