Antiangiogenic activity of deoxoartemisinin derivatives on chorioallantoic membrane

Non acetal-type derivatives at C-12 of artemisinin and their novel dimers including a fullerene conjugate were synthesized and some of them showed potent in vivo antiangiogenic activity on chorioallantoic membrane higher than or comparable to those of fumagillin and thalidomide.

Nonacetal-type derivatives of artemisinin and their novel dimers were synthesized and some of them showed potent in vivo antiangiogenic activity on chorioallantoic membrane higher than or comparable to those of fumagillin and thalidomide.Figure optionsDownload as PowerPoint slide