کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1367946 | 981655 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Anxiolytic effects of benzalphthalides
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Anxiolytic effects induced by benzalphthalides on mice have been evaluated. The evaluation was based on the spent time and the number of entries of animals into the open arms in the elevated plus maze test. Single administration of benzalphthalides 1 and 11 induced significant increments in both parameters, thus revealing their potentiality as new leads for the development of non-benzodiazepinic and non-nitrogenated antianxiety agents.
The anxiolytic activities of 12 benzalphthalides have been evaluated in the elevated plus maze test in mice. Two compounds showed significant activity.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 15, Issue 15, 1 August 2005, Pages 3483–3486
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 15, Issue 15, 1 August 2005, Pages 3483–3486
نویسندگان
Alejandro Zamilpa, Maribel Herrera-Ruiz, Esther del Olmo, José L. López-Pérez, Jaime Tortoriello, Arturo San Feliciano,