Synthesis and anti-inflammatory activity of novel biscoumarin–chalcone hybrids

A series of synthesized novel biscoumarin–chalcone hybrids were evaluated for their anti-inflammatory and antioxidant activity. The tested compounds significantly inhibit the carrageenin induced paw oedema in albino rats and also exhibit important scavenging activities. These compounds thus constitute an interesting template for the design of new therapeutic tools against inflammation.

Synthesis and anti-inflammatory activity of novel biscoumarin–chalcone hybrids are reported.Figure optionsDownload as PowerPoint slide