کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1371923 981860 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Ultrasmall particle of iron oxide—RGD peptidomimetic conjugate: synthesis and characterisation
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Ultrasmall particle of iron oxide—RGD peptidomimetic conjugate: synthesis and characterisation
چکیده انگلیسی

Ultrasmall particles of iron oxide (USPIOs) coated with 3,3′-bis(phosphonate)propionic acid were covalently coupled to a home-made Arg-Gly-Asp (RGD) peptidomimetic molecule via a short oligoethyleneglycol (OEG) spacer. The conjugation rate was measured by X-ray photoelectron spectroscopy (XPS). The particle size and magnetic characteristics were kept. Our novel conjugate targeted efficiently Jurkat cells (increase of 229% vs the control).

USPIO–peptidomimetic conjugate targeting Jurkat cells.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 20, Issue 6, 15 March 2010, Pages 1861–1865
نویسندگان
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