کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1371931 981860 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Heterocyclic acetamide and benzamide derivatives as potent and selective β3-adrenergic receptor agonists with improved rodent pharmacokinetic profiles
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Heterocyclic acetamide and benzamide derivatives as potent and selective β3-adrenergic receptor agonists with improved rodent pharmacokinetic profiles
چکیده انگلیسی

A series of amide derived β3-adrenergic receptor (AR) agonists is described. The discovery and optimization of several series of compounds derived from 1, is used to lay the SAR foundation for second generation β3-AR agonists for the treatment of overactive bladder.

Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 20, Issue 6, 15 March 2010, Pages 1895–1899
نویسندگان
, , , , , , , , , , , , , , , ,