کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1372468 981870 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Substituted tetrahydro-β-carbolines as potential agents for the treatment of human papillomavirus infection
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Substituted tetrahydro-β-carbolines as potential agents for the treatment of human papillomavirus infection
چکیده انگلیسی

The identification and optimization of a series of substituted tetrahydro-β-carbolines with potent activity against human papillomavirus is described. Structure–activity studies focused on the substitution pattern and chirality of the β-carboline ring system are discussed. Optimization of these parameters led to compounds with antiviral activities in the low nanomolar range.

The identification and optimization of a series of substituted tetrahydro-β-carbolines with potent activity against human papillomavirus is described. Structure–activity studies focused on the substitution pattern and chirality of the β-carboline ring system are discussed. Optimization of these parameters led to compounds with antiviral activities in the low nanomolar range.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 20, Issue 1, 1 January 2010, Pages 256–259
نویسندگان
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