کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1372753 981881 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reproducible enrichment of extracellular heat shock proteins from blood serum using monomeric avidin
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Reproducible enrichment of extracellular heat shock proteins from blood serum using monomeric avidin
چکیده انگلیسی

Extracellular heat shock proteins (eHsps) in blood circulation have been associated with various diseases, including cancer. However, the lack of methods to enrich eHsps from serum samples has hampered the characterization of eHsps. This Letter presents our serendipitous finding that the monomeric avidin resin can serve as an affinity resin to enrich eHsps from blood serum. Biochemical mechanism of this eHsp enrichment as well as implications in biomarker discovery is discussed.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 21, Issue 14, 15 July 2011, Pages 4134–4137
نویسندگان
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