Discovery and optimization of novel 4-[(aminocarbonyl)amino]-N-[4-(2-aminoethyl)phenyl]benzenesulfonamide ghrelin receptor antagonists

This Letter describes optimization of ghrelin receptor antagonists and inverse agonists starting from a screening hit.

This Letter describes optimization of ghrelin receptor antagonists and inverse agonists starting from a screening hit.Figure optionsDownload as PowerPoint slide