کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1373009 981887 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Radiolytic transformation of rotenone with potential anti-adipogenic activity
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Radiolytic transformation of rotenone with potential anti-adipogenic activity
چکیده انگلیسی

Radiolytic transformation of the isoflavonoid rotenone (1) with γ-irradiation afforded two new degraded products, rotenoisins A (2) and (3). The structures of the two new rotenone derivatives were elucidated on the basis of spectroscopic methods. The new products 2 and 3 exhibited significantly enhanced inhibitory activities against pancreatic lipase and adipocyte differentiation in 3T3-L1 cells when compared to parent rotenone.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 23, Issue 4, 15 February 2013, Pages 1099–1103
نویسندگان
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