New biologically active epidioxysterols from Stereum hirsutum

From the fungus Stereum hirsutum have been isolated and identified two new epidioxysterols 1, 4, together with two known ones 2 and 3. Their structures were elucidated on the basis of spectroscopic analysis and chemical reactions. Epidioxysterols 1–4 have been shown to possess a significant activity against Mycobacterium tuberculosis.

From the fungus Stereum hirsutum have been isolated and identified four epidioxysterols. Their structures were elucidated on the basis of spectroscopic analysis and chemical reactions. Epidioxysterols were found to show significant activity against Mycobacterium tuberculosis.Figure optionsDownload as PowerPoint slide