In vitro cytotoxicity study on platinum (II) complexes with epoxysuccinates as leaving groups

Ten new cisplatin-type platinum complexes with epoxysuccinates as leaving groups have been synthesized and structurally characterized. The in vitro cytotoxic activities of compounds toward SPC-A1 human lung adenocarcinoma cell line and BGC823 human stomach adenocarcinoma cell line have been determined.