کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1373750 | 981905 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Novel pyridopyrimidine derivatives as inhibitors of stable toxin a (STa) induced cGMP synthesis
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Novel pyridopyrimidine derivatives as inhibitors of stable toxin a (STa) induced cGMP synthesis Novel pyridopyrimidine derivatives as inhibitors of stable toxin a (STa) induced cGMP synthesis](/preview/png/1373750.png)
چکیده انگلیسی
A series of pyridopyrimidine derivatives were synthesized and evaluated for their ability to inhibit cyclic nucleotide synthesis in the presence of stable toxin a of Escherichia coli. The structure activity relationships around the basic core structure were examined and examples with better activity and potentially better pharmacological properties are presented.
A series of pyridopyrimidine derivatives were synthesized and evaluated for their ability to inhibit cyclic nucleotide synthesis in the presence of stable toxin a of Escherichia coli.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 19, Issue 11, 1 June 2009, Pages 3067–3071
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 19, Issue 11, 1 June 2009, Pages 3067–3071
نویسندگان
Eric A. Tanifum, Alexander Y. Kots, Byung-Kwon Choi, Ferid Murad, Scott R. Gilbertson,