کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1374397 | 981918 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Functional organisation and gain of activity: The case of the antibacterial tetra-para-guanidinoethyl-calix[4]arene
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Functional organisation and gain of activity: The case of the antibacterial tetra-para-guanidinoethyl-calix[4]arene Functional organisation and gain of activity: The case of the antibacterial tetra-para-guanidinoethyl-calix[4]arene](/preview/png/1374397.png)
چکیده انگلیسی
The antibacterial activities of the para-guanidinoethylphenol and of its cyclic tetramer, the tetra-para-guanidinoethyl-calix[4]arene, have been evaluated on reference Gram-positive and Gram-negative bacteria. Antibiotic disk diffusion assays completed by micromethod technique were employed to determine if a synergistic effect could be expected from the spatial organisation of the monomer into its cyclic tetrameric analogue. Disk diffusion assays and microdilution experiments revealed better properties for the calixarene species, with a real and important gain of activity with regards to the monomer.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 11, 1 June 2006, Pages 2960–2963
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 11, 1 June 2006, Pages 2960–2963
نویسندگان
Maxime Mourer, Raphaël E. Duval, Chantal Finance, Jean-Bernard Regnouf-de-Vains,