کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1374716 | 981923 | 2006 | 4 صفحه PDF | دانلود رایگان |
A novel acromelic acid analogue containing a phenyl group possessing two different types of azido functional groups, of which one is the aromatic N3 acting as a photoaffinity group to bind to a target protein by photoirradiation and the other is alkyl N3 group which survives photolysis acting as a detecting group through the Staudinger–Bertozzi reaction to identify the ligated product, was designed and synthesized as a radioisotope-free biochemical probe potentially for studies on kainoid receptors.
A novel bis-azido-containing acromelic acid analogue with the aromatic N3 acting as a photoaffinity group and the alkyl N3 group acting as a detecting group was designed and synthesized as a potential radioisotope-free biochemical probe for studies on kainoid receptors.Figure optionsDownload as PowerPoint slide
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 9, 1 May 2006, Pages 2433–2436