کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1374961 981928 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Factor VIIa inhibitors: Improved pharmacokinetic parameters
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Factor VIIa inhibitors: Improved pharmacokinetic parameters
چکیده انگلیسی

Efforts to improve the potency and pharmacokinetic properties of small molecule factor VIIa inhibitors are described. Small structural modifications to existing leads allow the modulation of half-life and clearance, potentially making these compounds suitable candidates for drug development.

Efforts to improve the potency and pharmacokinetic properties of small molecule factor VIIa inhibitors are described. Small structural modifications to existing leads allow the modulation of half-life and clearance, potentially making these compounds suitable candidates for drug development.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 8, 15 April 2006, Pages 2243–2246
نویسندگان
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