کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1375067 | 981931 | 2009 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
l-Prolinol as a highly enantioselective catalyst for Michael addition of cyclohexanone to nitroolefins
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: l-Prolinol as a highly enantioselective catalyst for Michael addition of cyclohexanone to nitroolefins l-Prolinol as a highly enantioselective catalyst for Michael addition of cyclohexanone to nitroolefins](/preview/png/1375067.png)
چکیده انگلیسی
Though many chiral amines such as l-proline and its derivatives have proven to be versatile catalysts in many reactions, l-prolinol was seldom used as organocatalyst for reactions. Herein, we report the first l-prolinol catalyzed asymmetric Michael addition of cyclohexanone to nitroolefins in the presence of benzoic acid to afford Michael adducts with high diastereoselectivities (87:13–>99:1) and enantioselectivities (82–96%).
The first l-prolinol catalyzed asymmetric Michael addition of cyclohexanone to nitroolefins in the presence of benzoic acid to afford Michael adducts with high diastereoselectivities (87:13–>99:1) and enantioselectivities (82–96%) was described.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 19, Issue 14, 15 July 2009, Pages 3915–3918
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 19, Issue 14, 15 July 2009, Pages 3915–3918
نویسندگان
Pei Juan Chua, Bin Tan, Xiaofei Zeng, Guofu Zhong,